Special issue focuses on leprosy | Vol. 107(suppl. I) December 2012

 

Dermal inflammatory accumulation predominantly composed of Mycobacterium leprae-loaded macrophages in a cutaneous lepromatous lesion
(Wade staining 1,000X). Image by Sérgio Luiz Gomes Antunes.

 

 

 

 

 

 

CONTENTS

ARTICLES

Foreword
- Claude Pirmez, Milton Ozório Moraes, John S Spencer
[ Pdf ]

Leprosy frequency in the world, 1999-2010
- Maria Lúcia Fernandes Penna, Gerson Oliveira Penna
[ Pdf ]

Hansen’s disease: a vanishing disease?
- Sinésio Talhari, Maria Aparecida de Faria Grossi, Maria Leide WDR de Oliveira, Bernardo Gontijo, Carolina Talhari, Gerson Oliveira Penna
[ Pdf ]

Historic aspects of human susceptibility to leprosy and the risk of conjugal transmission
- M Patricia Joyce
[ Pdf ]

A clinical trial for uniform multidrug therapy for leprosy patients in Brazil: rationale and design
- Gerson Oliveira Penna, Maria Araci de Andrade Pontes, Rossilene Cruz, Heitor de Sá Gonçalves, Maria Lúcia Fernandes Penna, Samira Bührer-Sékula
[ Pdf ][ Supplementary data 1][ Supplementary data 2]

Leprosy, a neglected disease that causes a wide variety of clinical conditions in tropical countries
- Norma Tiraboschi Foss, Ana Carolina Fragoso Motta
[ Pdf ]

Erythema multiforme in leprosy
- Alice Machado Miranda, Sérgio Luiz Gomes Antunes, José Augusto Costa Nery, Anna Maria Sales, Mario José dos Santos Pereira, Euzenir Nunes Sarno
[ Pdf ]

The role of human T cell lymphotrophic virus type 1, hepatitis B virus and hepatitis C virus coinfections in leprosy
- Paulo Roberto Lima Machado, Warren D Johnson, Marshall J Glesby
[ Pdf ]

Characteristics of leprosy diagnosed through the surveillance of contacts: a comparison with index cases in Rio de Janeiro, 1987-2010
- Mariana de Andrea Hacker, Nadia Cristina Duppre, José Augusto Costa Nery, Anna Maria Sales, Euzenir Nunes Sarno
[ Pdf ]

Unveiling healthy carriers and subclinical infections among household contacts of leprosy patients who play potential roles in the disease chain of transmission
- Sérgio Araújo, Janaína Lobato, Érica de Melo Reis, Dulcinéa Oliveira Bernardes Souza, Maria Aparecida Gonçalves, Adeilson Vieira Costa, Luiz Ricardo Goulart, Isabela Maria Bernardes Goulart
[ Pdf ]

High rates of undiagnosed leprosy and subclinical infection amongst school children in the Amazon Region
- Josafá Gonçalves Barreto, Layana de Souza Guimarães, Marco Andrey Cipriani Frade, Patricia Sammarco Rosa, Claudio Guedes Salgado
[ Pdf ]

Cutaneous lesions sensory impairment recovery and nerve regeneration in leprosy patients
- Ximena Illarramendi, Emanuel Range, Alice Machado Miranda, Ana Claudia Ribeiro de Castro, Giselle de Oliveira Magalhães, Sérgio Luiz Gomes Antunes
[ Pdf ]

Brazilian clinical trial of uniform multidrug therapy for leprosy patients - the correlation between clinical disease types and adverse effects
- Heitor de Sá Gonçalves, Maria Araci de Andrade Pontes, Samira Bührer-Sékula, Rossilene Cruz, Paulo Cesar Almeida, Maria Elisabete Amaral de Moraes, Gerson Oliveira Penna
[ Pdf ]

Identification of serological biomarkers of infection, disease progression and treatment efficacy for leprosy
- John S Spencer, Malcolm S Duthie, Annemieke Geluk, Marivic F Balagon, Hee Jin Kim, William H Wheat, Delphi Chatterjee, Mary Jackson, Wei Li, Jade N Kurihara, Armi Maghanoy, Irene Mallari, Paul Saunderson, Patrick J Brennan, Hazel M Dockrell
[ Pdf ]

Serologic follow-up of IgG responses against recombinant mycobacterial proteins ML0405, ML2331 and LID-1 in a leprosy hyperendemic area in Venezuela
- Elsa Rada, Malcolm S Duthie, Steven G Reed, Nacarid Aranzazu, Jacinto Convit
[ Pdf ]

Lepromatous leprosy patients produce antibodies that recognise non-bilayer lipid arrangements containing mycolic acids
- Isabel Baeza, Carlos Wong-Baeza, Esther Valerdi, Jeanet Serafin-Lopez, Miguel Ibáñez, Sergio Estrada-Parra, Carlos Wong, Iris Estrada-Garcia
[ Pdf ][ Supplementary data ]

Seroreactivity to new Mycobacterium leprae protein antigens in different leprosy-endemic regions in Brazil
- Emerith Mayra Hungria, Regiane Morillas de Oliveira, Ana Lúcia Osório Maroclo de Souza, Maurício Barcelos Costa, Vânia Nieto Brito de Souza, Eliane Aparecida Silva, Fátima Regina Vilani Moreno, Maria Esther Salles Nogueira, Maria Renata Sales Nogueira Costa, Sônia Maria Usó Ruiz Silva, Samira Bührer-Sékula, Steven G Reed, Malcolm S Duthie, Mariane Martins de Araújo Stefani
[ Pdf ]

Mycobacterium leprae virulence-associated peptides are indicators of exposure to M. leprae in Brazil, Ethiopia and Nepal
- Kidist Bobosha, Sheila Tuyet Tang, Jolien J van der Ploeg-van Schip, Yonas Bekele, Marcia VSB Martins, Ole Lund, Kees LMC Franken, Saraswoti Khadge, Maria Araci de Andrade Pontes, Heitor de Sá Gonçalves, Jemal Hussien, Pratibha Thapa, Chhatra B Kunwar, Deanna A Hagge, Abraham Aseffa, Maria Cristina Vidal Pessolani, Geraldo MB Pereira, Tom HM Ottenhoff, Annemieke Geluk
[ Pdf ]

Comparison of two rapid tests for anti-phenolic glycolipid-I serology in Brazil and Nepal
- Mariane Martins de Araújo Stefani, Adriano Badotti Grassi, Lucas Henrique Sampaio, Ana Lúcia Osório Maroclo de Sousa, Maurício Barcelos Costa, Pauline Scheelbeek, Kapil D Neupane, Deanna A Hagge, Murdo Macdonald, Sang-Nae Cho4, Linda Oskam, Samira Bührer-Sékula
[ Pdf ]

Genetics of leprosy reactions: an overview
- Vinicius Fava, Marianna Orlova, Aurélie Cobat, Alexandre Alcaïs, Marcelo Mira, Erwin Schurr
[ Pdf ]

Genotyping of Mycobacterium leprae present on Ziehl-Neelsen-stained microscopic slides and in skin biopsy samples from leprosy patients in different geographic regions of Brazil
- Amanda Nogueira Brum Fontes, Harrison Magdinier Gomes, Marcelo Ivens de Araujo, Edson Cláudio Araripe de Albuquerque, Ida Maria Foschiani Dias Baptista, Maria Manuela da Fonseca Moura, Denise Silva Rezende, Maria Cristina Vidal Pessolani, Flávio Alves Lara, Maria Araci de Andrade Pontes, Heitor de Sá Gonçalves, Norma Lucena-Silva, Euzenir Nunes Sarno, Varalakshmi D Vissa, Patrick J Brennan, Philip Noel Suffys
[ Pdf ]

Association analysis of human leukocyte antigen class II (DRB1) alleles with leprosy in individuals from São Luís, state of Maranhão, Brazil
- Rita da Graça Carvalhal Frazão Corrêa, Dorlene Maria Cardoso de Aquino, Arlene de Jesus Mendes Caldas, Humberto de Oliveira Serra, Fábio França Silva, Maxwellem de Jesus Costa Ferreira, Elton Jonh Freitas Santos, Emygdia Rosa Rêgo Barros Pires Leal Mesquita
[ Pdf ]

Deciphering the contribution of lipid droplets in leprosy: multifunctional organelles with roles in Mycobacterium leprae pathogenesis
- Katherine Antunes de Mattos, Euzenir Nunes Sarno, Maria Cristina Vidal Pessolani, Patricia T Bozza
[ Pdf ]

Differential expression of the costimulatory molecules CD86, CD28, CD152 and PD-1 correlates with the host-parasite outcome in leprosy
- Maria de Lourdes Palermo, Maria Ângela Bianconcini Trindade, Alberto José da Silva Duarte, Camila Rodrigues Cacere, Gil Benard
[ Pdf ]

Mycobacterial laminin-binding histone-like protein mediates collagen-dependent cytoadherence
- André Alves Dias, Dominique Raze, Cristiana Soares de Lima, Maria Angela de Melo Marques, Hervé Drobecq, Anne-Sophie Debrie, Michelle Lopes Ribeiro-Guimarães, Franck Biet, Maria Cristina Vidal Pessolani
[ Pdf ][ Supplementary data ]

Increased hepcidin expression in multibacillary leprosy
- Vânia Nieto Brito de Souza, Tatiana Salles de Souza Malaspina, Ana Paula Campanelli, Cássio Ghidella, Somei Ura, Dirceu Dalpino, Dejair Caitano do Nascimento, Ana Carla Pereira Latini
[ Pdf ]

The potential for vaccination in leprosy elimination: new tools for targeted interventions
- Malcolm S Duthie, Paul Saunderson, Steven G Reed
[ Pdf ]

Insights from animal models on the immunogenetics of leprosy - A Review
- Linda B Adams, Maria T Pena, Rahul Sharma, Deanna A Hagge, Erwin Schurr, Richard W Truman
[ Pdf ]

Mycobacterium leprae in six-banded (Euphractus sexcinctus) and nine-banded armadillos (Dasypus novemcinctus) in Northeast Brazil
- Cristiane Cunha Frota, Luana Nepomuceno Costa Lima, Adalgiza da Silva Rocha, Philip Noel Suffys, Benedito Neilson Rolim, Laura Cunha Rodrigues, Maurício Lima Barreto, Carl Kendall, Ligia Regina Sansigolo Kerr
[ Pdf ]

 

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