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       Author Guidelines

The manuscript should be prepared using standard word processing software and should be printed (font size 12) double-spaced throughout the text, figure captions, and references, with margins of at least 3 cm. The figures should come in the extension tiff, with a minimum resolution of 300 dpi. Tables and legends to figures must be submitted all together in a single file. Figures, must be uploaded separately as supplementary file.

The manuscript should be arranged in the following order:

Running title: with up to 40 characters (letters and spaces)

Title: with up to 250 characters

Author's names: without titles or graduations

Intitutional affiliations: full address of the corresponding author only

Summary: up to 200 words (100 words in case of short communications). It should emphasize new and important aspects of the study or observations.

Key words: 3-6 items must be provided. Terms from the Medical Subject Headings (Mesh) list of Index Medicus should be used.

Sponsorships: indicating the sources of financial support and change of address

Introduction: should set the purpose of the study, give a brief summary (not a review) of previous relevant works, and state what new advance has been made in the investigation. It should not include data or conclusions from the work being reported.

Materials and Methods: should briefly give clear and sufficient information to permit the study to be repeated by others. Standard techniques need only be referenced.

Ethics: when reporting experiments on human subjects, indicate whether the procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional or regional) and with the Helsinki Declaration of 1975, as revised in 1983. When reporting experiments on animals, indicate whether the institution's or a national research council's guide for, or any national law on the care and use of laboratory animals was followed.

Results: should be a concise account of the new information discovered, with the least personal judgement. Do not repeat in text all the data in the tables and illustrations.

Discussion: should be limited to the significance of the new information and relate the new findings to existing knowledge. Only unavoidable citations should be included.

Acknowledgements: should be short and concise, and restricted to those absolutely necessary.

References: must be accurate. Only citations that appear in the text should be referenced. Unpublished papers, unless accepted for publication, should not be cited. Work accepted for publication should be referred to as "in press" and a letter of acceptance of the journal must be provided. Unpublished data should only be cited in the text as "unpublished observations", and a letter of permission from the author must be provided. The references at the end of the paper should be arranged in alphabetic order according to the surname of the first author.

The titles of journals should be abbreviated according to the style used in the Index Medicus. Consult:

In the text use authors' surname and date:
  Lutz (1910) or (Lutz 1910)


With two authors it is:
(Lutz & Neiva 1912) or Lutz and Neiva (1912)
  When there are more than two authors, only the first is mentioned:
Lutz et al. (1910) or (Lutz et al. 1910).

At the end of the paper use the following styles:

Journal article
Chagas C, Villela E 1922. Forma cardiaca da tripanosomiase americana. Mem Inst Oswaldo Cruz 14: 15-61.

Book and Thesis
Forattini OP 1973. Entomologia Médica. Psychodidae, Phlebotominae, Leishmaniose, Bartonelose, Vol. IV, Edgard Blucher, São Paulo, 658 pp.

Morel CM 1983. Genes and Antigens of Parasites. A Laboratory Manual, 2nd ed., Fundação Oswaldo Cruz, Rio de Janeiro, xxii + 580 pp.

Mello-Silva CC 2005. Controle alternativo e alterações fisiológicas em Biomphalaria glabrata (Say, 1818), hospedeiro intermediário de Schistosoma mansoni Sambom, 1907 pela ação do látex de Euphorbia splendens var. hislopii N.E.B (Euphorbiaceae), PhD Thesis, Universidade Federal Rural do Rio de Janeiro, Seropédica, 85 pp.

Chapter in book
Cruz OG 1911. The prophylaxis of malaria in central and southern Brasil. In R Ross, The Prevention of Malaria, John Murray, London, p. 390-398.

Journal article on the Internet
Abood S. Quality improvement initiative in nursing homes: the ANA acts in an advisory role. Am J Nurs [serial on the Internet]. 2002 Jun [cited 2002 Aug 12];102(6):[about 3 p.]. Available from:

Monograph on the Internet
Foley KM, Gelband H, editors. Improving palliative care for cancer [monograph on the Internet]. Washington: National Academy Press; 2001 [cited 2002 Jul 9]. Available from: http://www.nap.edu/books/0309074029/html/.

Homepage/Web site
Cancer-Pain.org [homepage on the Internet]. New York: Association of Cancer Online Resources, Inc.; c2000-01 [updated 2002 May 16; cited 2002 Jul 9]. Available from: http://www.cancer-pain.org/.

Part of a homepage/Web site
American Medical Association [homepage on the Internet]. Chicago: The Association; c1995-2002 [updated 2001 Aug 23; cited 2002 Aug 12]. AMA Office of Group Practice Liaison; [about 2 screens]. Available from:


Open database:
Who's Certified [database on the Internet]. Evanston (IL): The American Board of Medical Specialists. c2000 - [cited 2001 Mar 8]. Available from: http://www.abms.org/newsearch.asp

Closed database:
Jablonski S. Online Multiple Congenital Anomaly/Mental Retardation (MCA/MR) Syndromes [database on the Internet]. Bethesda (MD): National Library of Medicine (US). c1999 [updated 2001 Nov 20; cited 2002 Aug 12]. Available from: http://www.nlm.nih.gov/mesh/jablonski/syndrome_title.html

Part of a database on the Internet
MeSH Browser [database on the Internet]. Bethesda (MD): National Library of Medicine (US); 2002 - [cited 2003 Jun 10]. Meta-analysis; unique ID: D015201; [about 3 p.]. Available from:
http://www.nlm.nih.gov/mesh/MBrowser.html Files updated weekly. Updated June 15, 2005

Illustrations: figures and tables must be understandable without reference to the text.
Figures: presented in tiff format with a minimum of 300 dpi and photographs must be sharply focused, well contrasted, and if mounted onto a plate, the figures should be numbered consecutively with Arabic numbers. Magnification must be indicated by a line or bar in the figure, and referenced, if necessary in the caption (e.g., bar = 1 mm). Plates and line figures should either fit one column (8 cm) or the full width (16.5 cm) of the page and should be shorter than the page length to allow inclusion of the legend. Letters and numbers on figures should be of a legible size upon reduction or printing. A colour photograph illustrates the cover of each issue of the Journal and authors are invited to submit illustrations with legends from their manuscript for consideration for the cover
- Tables should supplement, not duplicate, the text and should be numbered with Roman numerals. A short descriptive title should appear above each table, with any explanations or footnotes (identified with a, b, c, etc.) below.

Technical Notes: Technical Notes should communicate rapidly single novel techniques or original technical advances. The entire note should occupy no more than three printed pages including figures and/or tables (it means around 10 double-spaced typed Word file maximum). The text must not be not divided into sections. Therefore, the state of art must be very briefly presented; results must be rapidly presented and discussed at a time. Complementary tables and figures may be published as supplementary data. References must be limited to few essential ones and cited at the end of the note, using the same format as in full papers. A brief summary and three key words must be provided.

Short communications: should communicate rapidly single results or techniques. They should occupy no more than three printed pages including figures and/or tables. They should not contain excessive references. References should be cited at the end of the paper using the same format as in full papers. A brief summary and three key words must be provided.

Alternative format: manuscripts may be submitted following the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals" produced by the International Committee of Medical Journal Editors also known as the Vancouver Style. In this case, authors should follow the guidelines in the fifth edition (Annals of Internal Medicine 1997; 126: 36-47, or at the website http://www.acponline.org/journals/resource/unifreqr/htm) and will be responsible for modifying the manuscript where it differs from the instructions given here, if the manuscript is accepted for publication.
Authors should also follow the Uniform Requirements for any guidelines that are omitted in these Instructions.

In case of clinical trials itís mandatory to inform the registration number of the REBEC platform.

A statement that the data/results of the manuscript are not plagiarism and have not been published elsewhere.

Once a paper is accepted for publication, the authors must provide:

an affidavit, provided by the Editorial Office, signed by all authors. Authors from different countries or institutions may sign in different sheets containing the same basic statement;
a copyright assignment form, provided by the Editorial Office, signed by the corresponding author.
Page charges: there will be no page charges.
Proofs: one set of page proofs will be supplied for the author to check for typesetting accuracy, to be returned by the stipulated date. No changes to the original manuscript will be allowed at this stage.