MEM INST OSWALDO CRUZ, RIO DE JANEIRO, Vol. 112 | 2017
PAGES: DOI: 10.1590/0074-02760170339 Short communication
Evaluation of melanin production by Sporothrix luriei

Ingrid Ludmilla Rodrigues Cruz, Maria Helena Galdino Figueiredo-Carvalho, Rosely Maria Zancopé-Oliveira, Rodrigo Almeida-Paes+

Fundação Oswaldo Cruz-Fiocruz, Instituto Nacional de Infectologia Evandro Chagas, Laboratório de Micologia, Rio de Janeiro, RJ, Brasil

Abstract

There is a paucity of studies on the cell biology of Sporothrix luriei, the less common of the pathogenic Sporothrix species worldwide. The production of DHN-melanin, eumelanin, and pyomelanin were evaluated on the mycelial and yeast forms of the S. luriei ATCC 18616 strain. The mycelial form of this species produced only pyomelanin, which protected the fungus against environmental stressors such as ultraviolet light, heat, and cold. The yeast form was unable to produce any of the tested melanin types. The lack of melanin in the parasitic form of S. luriei may be an explanation for its low frequency in human infections.

Financial support: CNPq (grant No. 449184/2014-5).
RA-P and RMZ-O are supported in part by CNPq (grant No. 305487/2015-9 and 304976/2013-0, respectively).
+ Corresponding author: This e-mail address is being protected from spambots. You need JavaScript enabled to view it.
Received 21 August 2017
Accepted 25 September 2017

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