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MEM INST OSWALDO CRUZ, RIO DE JANEIRO, 112(7) July 2017
PAGES: 514-516 DOI: 10.1590/0074-02760160546 Genome announcement and Highlights
Complete plasmid sequence carrying type IV-like and type VII secretion systems from an atypical mycobacteria strain

Sergio Mascarenhas Morgado+, Michel Abanto Marín, Fernanda S Freitas, Erica Lourenço Fonseca, Ana Carolina Paulo Vicente

Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Genética Molecular de Microrganismos, Rio de Janeiro, RJ, Brasil

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Abstract

The genus Mycobacterium is highly diverse and ubiquitous in nature, comprehending fast- and slow-growing species with distinct impact in public health. The plasmid-mediated horizontal gene transfer represents one of the major events in bacteria evolution. Here, we report the complete sequence of a 160,489 bp circular plasmid (pCBMA213_2) from an atypical and fast-growing environmental mycobacteria. This is a unique plasmid, in comparison with the characterised mycobacteria plasmids, harboring a type IV-like and ESX-P2 type VII secretion systems. pCBMA213_2 can be further explored for evolutionary and conjugation studies as well as a tool to manipulate DNA within this bacteria genus.

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Financial support: CAPES, PNPD-CAPES (fellowships), CNPq, IOC-FIOCRUZ (grants).
+ Corresponding author: This e-mail address is being protected from spambots. You need JavaScript enabled to view it.
Received 20 December 2016
Accepted 28 January 2017