MEM INST OSWALDO CRUZ, RIO DE JANEIRO, FAST TRACK
PAGES: DOI: 10.1590/0074-02760180036 Short communication
Imported case of Dengue virus 3 Genotype I in Rio de Janeiro state, Brazil

Marcos César Lima de Mendonça1+, Maria Angelica Mares-Guia1, Cintia Damasceno dos Santos Rodrigues1, Carolina Cardoso dos Santos1, Flavia Lowen Levy Chalhoub1, Eliane Saraiva Machado Araújo1, Alexandre Otávio Chieppe2, Rita Maria Ribeiro Nogueira1, Ana Maria Bispo de Filippis1

1Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Flavivírus, Rio de Janeiro, RJ, Brazil
2Secretaria Estadual de Saúde do Rio de Janeiro

Abstract

The dengue virus (DENV), of genus Flavivirus (Flaviviridae), has four antigenically distinct serotypes, of which DENV-3 is classified into five genotypes. Here, we describe the detection of DENV-3 genotype I in sera of a Brazilian patient returning from Singapore to Rio de Janeiro, Brazil by using multiplex real-time RT-PCR, Sanger sequencing of the whole envelope protein, and phylogenetic analysis. The virus shares ancestry with those identified in Bali, Indonesia in 2015. Because of tourism and mass events occurring in the last four years (World Youth Day, World Cup, Olympics), arboviruses, such as Chikungunya genotype ECSA, DENV-4 Genotype I, and Zika, from other continents have been introduced in Brazil.

Corresponding author 
+ Marcos César Lima de Mendonça:  This e-mail address is being protected from spambots. You need JavaScript enabled to view it.

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